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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
25.15
Human Site:
Y292
Identified Species:
50.3
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
Y292
C
Q
K
K
I
R
I
Y
H
S
L
T
G
L
H
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
Y223
I
L
P
P
S
S
I
Y
P
S
V
L
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
Y292
C
Q
K
K
I
R
I
Y
H
S
L
T
G
L
H
Dog
Lupus familis
XP_531626
735
82556
Y292
C
Q
K
K
I
R
I
Y
H
S
L
V
G
L
H
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
Y293
C
Q
K
K
I
R
T
Y
H
S
L
T
G
L
H
Rat
Rattus norvegicus
P51556
727
82180
Y290
C
Q
K
K
I
R
T
Y
H
S
L
T
G
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
Y330
C
H
K
T
I
K
C
Y
Q
G
L
T
G
L
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
L295
C
Q
K
K
I
K
S
L
H
G
L
T
G
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
A470
K
C
R
K
R
I
K
A
Y
H
G
I
T
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
K354
T
V
G
V
F
Q
G
K
G
C
R
W
C
H
N
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
Y760
C
K
K
S
I
K
S
Y
N
G
I
T
G
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
A298
T
G
P
T
V
N
G
A
H
A
V
L
E
N
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
60
N.A.
60
N.A.
6.6
N.A.
0
53.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
66.6
N.A.
20
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
9
0
0
9
0
0
% A
% Cys:
67
9
0
0
0
0
9
0
0
9
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
17
0
9
25
9
0
67
9
9
% G
% His:
0
9
0
0
0
0
0
0
59
9
0
0
0
9
59
% H
% Ile:
9
0
0
0
67
9
34
0
0
0
9
9
0
0
0
% I
% Lys:
9
9
67
59
0
25
9
9
0
0
0
0
0
9
0
% K
% Leu:
0
9
0
0
0
0
0
9
0
0
59
17
0
59
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
9
0
0
0
0
9
9
% N
% Pro:
0
0
17
9
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
50
0
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
9
42
0
0
0
0
9
0
0
0
9
% R
% Ser:
0
0
0
9
9
9
17
0
0
50
0
0
0
9
9
% S
% Thr:
17
0
0
17
0
0
17
0
0
0
0
59
9
0
0
% T
% Val:
0
9
0
9
9
0
0
0
0
0
17
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _